Abstract Chemistry is everything and everywhere, as a result, chemistry offers wide varieties of business opportunities for small and medium enterprises development like any other discipline. From the perspective of students, starting a new firm is a complicated decision due to high uncertainty and perceived risk. There are many factors that can support or hinder the students’ decision to start their own business. Therefore, entrepreneurial intention of chemistry education students in tertiary educational institutions in Kano state were surveyed with structured questionnaire. Research questions were raised and hypotheses tested using descriptive and inferential statistical tools. Motivation to go into private business included quest to gain more money, influence from family and the urge to be an independent person. Barriers such as lack of initial capital outlay (seed capital) and lack of guidance proved to be highly significant hindrances. Based on the findings, it was recommended among others, that all stakeholders should create and strengthen entrepreneurial education specifically for tertiary educational institutions in Nigeria.

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